Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11835084 | 0.94 | MAPT (0.60) | MAPTKDM4ETSHRHSD17B10KMT2A | |
| SCHEMBL11843862 | 0.82 | KDM4E (0.47) | MAPTKDM4ETSHRHSD17B10KMT2A | |
| Hydrochloric Acid SCHEMBL11834842 | 0.81 | KDM4E (0.46) | MAPTKDM4ETSHRHSD17B10KMT2A | |
| SCHEMBL11832822 | 0.80 | KDM4E (0.63) | MAPTKDM4ETSHRHSD17B10KMT2A | |
| SCHEMBL11832928 | 0.79 | MAPT (0.57) | MAPTKDM4ETSHRHSD17B10KMT2A | |
| SCHEMBL11842021 | 0.78 | MAPT (0.57) | MAPTKDM4ETSHRHSD17B10KMT2A | |
| Hydrochloric Acid SCHEMBL11837552 | 0.78 | MAPT (0.56) | MAPTKDM4ETSHRHSD17B10KMT2A | |
| SCHEMBL15631883 | 0.77 | MAPT (1.00) | MAPTKDM4ETSHRHSD17B10KMT2A | |
| Hydrochloric Acid SCHEMBL11837384 | 0.77 | MAPT (0.56) | MAPTKDM4ETSHRHSD17B10KMT2A | |
| SCHEMBL15631909 | 0.76 | MAPT (0.69) | MAPTKDM4ETSHRHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994890-A | TRANQUILIZERS, ANTIDEPRESSANTS, ANTIINFLAMMATORY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-11-30 | — | — | US | disclosed |