Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11845302 | 0.85 | KDM4E (0.53) | KMT2AKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL11832922 | 0.84 | KDM4E (0.72) | KMT2AKDM4EALDH1A1LMNAHTT | |
| Hydrochloric Acid SCHEMBL11837543 | 0.83 | KDM4E (0.70) | KMT2AKDM4EALDH1A1LMNAHTT | |
| SCHEMBL11834582 | 0.79 | KMT2A (0.55) | KMT2AKDM4EHSD17B10ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL11833084 | 0.78 | KMT2A (0.53) | KMT2AKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL11837486 | 0.77 | KMT2A (0.58) | KMT2AKDM4EHSD17B10ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL11835272 | 0.75 | KMT2A (0.57) | KMT2AKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL11846471 | 0.75 | KMT2A (0.50) | KMT2AKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL11841704 | 0.74 | KMT2A (0.49) | KMT2AKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL11841868 | 0.74 | KMT2A (0.52) | KMT2AKDM4EHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994890-A | TRANQUILIZERS, ANTIDEPRESSANTS, ANTIINFLAMMATORY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-11-30 | — | — | US | claimed |
| US-3994890-A | TRANQUILIZERS, ANTIDEPRESSANTS, ANTIINFLAMMATORY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-11-30 | — | — | US | disclosed |