Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.51 |
| ▸ | MERTK | Q12866 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8138785 | 0.84 | HSD17B10 (0.50) | HSD17B10KDM4ETSHRKMT2AALDH1A1 | |
| SCHEMBL11845306 | 0.83 | KDM4E (0.49) | HSD17B10KDM4ETSHRKMT2AALDH1A1 | |
| SCHEMBL11832928 | 0.83 | MAPT (0.57) | HSD17B10KDM4ETSHRKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11837552 | 0.82 | MAPT (0.56) | HSD17B10KDM4ETSHRKMT2AALDH1A1 | |
| SCHEMBL11834589 | 0.81 | KDM4E (0.63) | HSD17B10KDM4ETSHRKMT2AALDH1A1 | |
| SCHEMBL11832822 | 0.81 | KDM4E (0.63) | HSD17B10KDM4ETSHRKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11833093 | 0.80 | KDM4E (0.61) | HSD17B10KDM4ETSHRKMT2AALDH1A1 | |
| SCHEMBL27496805 | 0.79 | HSD17B10 (0.61) | HSD17B10KDM4ETSHRKMT2AALDH1A1 | |
| SCHEMBL11846475 | 0.79 | HSD17B10 (0.60) | HSD17B10KDM4ETSHRKMT2AALDH1A1 | |
| SCHEMBL11841873 | 0.77 | HSD17B10 (0.62) | HSD17B10KDM4ETSHRKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994890-A | TRANQUILIZERS, ANTIDEPRESSANTS, ANTIINFLAMMATORY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-11-30 | — | — | US | claimed |
| US-3994890-A | TRANQUILIZERS, ANTIDEPRESSANTS, ANTIINFLAMMATORY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-11-30 | — | — | US | disclosed |