Quercetin

Quercetin

SCHEMBL118425

O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12.O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 11/20 1.00
▸ KMT2A Q03164 11/20 1.00
▸ CYP1A2 P05177 8/20 1.00
▸ CYP3A4 P08684 8/20 1.00
▸ KDM4E B2RXH2 8/20 1.00
▸ HSD17B10 Q99714 8/20 1.00
▸ MAPT P10636 8/20 1.00
▸ CYP2C9 P11712 7/20 1.00
▸ RECQL P46063 7/20 1.00
▸ CYP1A1 P04798 7/20 1.00
▸ CYP1B1 Q16678 7/20 1.00
▸ XDH P47989 7/20 1.00
▸ FTO Q9C0B1 7/20 1.00
▸ ALOX15 P16050 6/20 1.00
▸ ABCB1 P08183 6/20 1.00
▸ APP P05067 6/20 1.00
▸ POLH Q9Y253 6/20 1.00
▸ POLB P06746 5/20 1.00
▸ TP53 P04637 5/20 1.00
▸ IPMK Q8NFU5 5/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quercetin SCHEMBL29351036 1.00 MEN1 (1.00) MEN1KMT2ACYP1A2CYP3A4KDM4E
Quercetin SCHEMBL29353785 1.00 MEN1 (1.00) MEN1KMT2ACYP1A2CYP3A4KDM4E
Quercetin SCHEMBL29723041 1.00 MEN1 (1.00) MEN1KMT2ACYP1A2CYP3A4KDM4E
Quercetin SCHEMBL17629824 1.00 MEN1 (1.00) MEN1KMT2ACYP1A2CYP3A4KDM4E
Quercetin SCHEMBL31507620 1.00 MEN1 (1.00) MEN1KMT2ACYP1A2CYP3A4KDM4E
Quercetin SCHEMBL19723 1.00 MEN1 (1.00) MEN1KMT2ACYP1A2CYP3A4KDM4E
Quercetin SCHEMBL22103 0.99 MEN1 (1.00) MEN1KMT2ACYP1A2CYP3A4KDM4E
Quercetin SCHEMBL6756842 0.99 MEN1 (0.97) MEN1KMT2ACYP1A2CYP3A4KDM4E
Quercetin SCHEMBL21585504 0.99 MEN1 (0.97) MEN1KMT2ACYP1A2CYP3A4KDM4E
Quercetin SCHEMBL21590136 0.99 MEN1 (0.97) MEN1KMT2ACYP1A2CYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104840508-A Acacia mearnsii leaf extract as well as preparation method and application of acacia mearnsii extract UNIV NANJING FORESTRY 2015-08-19 — — CN claimed
CN-118045062-A Protein-polysaccharide ternary composite nanoparticle loaded with quercetin, and preparation method and application thereof 合肥工业大学 2024-05-17 — — CN disclosed
CN-111836805-B Pyridine derivatives and their use for the treatment of HIV infection 吉利德科学公司 2023-07-14 — — CN disclosed
CN-115991708-A HIV inhibitor compounds 吉利德科学公司 2023-04-21 — — CN disclosed
CN-114874220-B 8-aminobenzene sulfonamide substituted tryptanthrin derivative and preparation and application thereof 安徽瀚海博兴生物技术有限公司 2023-04-21 — — CN disclosed
CN-114874220-A 8-aminobenzene sulfonamide substituted tryptanthrin derivative and preparation and application thereof 安徽瀚海博兴生物技术有限公司 2022-08-09 — — CN disclosed
CN-113712102-A Health tea and preparation process thereof 丛志弘 2021-11-30 — — CN disclosed
WO-2021237109-A1 COMBINATION THERAPY FOR TREATMENT OF VIRAL INFECTIONS TRAILHEAD BIOSYSTEMS INC. (US) 2021-11-25 — — WO disclosed
CN-112870184-A Application of rheum emodin in preparing medicine for treating or improving neurodegenerative diseases 澳门大学 2021-06-01 — — CN disclosed
CN-109999002-A A kind of preparation method of quercetin nano particle and its preparing the application on anti-breast cancer medicines 福州大学 2019-07-12 — — CN disclosed
US-20090325906-A1 Methods and compositions for therapeutic treatment LIMERICK BIOPHARMA, INC. 2009-12-31 — — US disclosed
WO-2009158031-A2 METHODS AND COMPOSITIONS FOR THERAPEUTIC TREATMENT LIMERICK BIOPHARMA, INC. (US) 2009-12-30 — — WO disclosed
US-20090176810-A1 COMPOSITION FOR SKIN EXTERNAL APPLICATION CONTAINING GALLOCATECHIN GALLATE FOR MOISTURIZING EFFECT ON THE SKIN AMOREPACIFIC CORPORATION (KR) 2009-07-09 — — US disclosed
EP-2068865-A2 METHODS AND COMPOSITIONS FOR THERAPEUTIC TREATMENT Limerick BioPharma, Inc. (US) 2009-06-17 — — EP disclosed
WO-2009018338-A2 PHOSPHORYLATED PYRONE ANALOGS AND METHODS LIMERICK BIOPHARMA, INC. (US) 2009-02-05 — — WO disclosed
WO-2009018326-A2 SOLUBLE PYRONE ANALOGS METHODS AND COMPOSITIONS LIMERICK BIOPHARMA, INC. (US) 2009-02-05 — — WO disclosed
WO-2008083160-A2 METHODS AND COMPOSITIONS FOR THERAPEUTIC TREATMENT LIMERICK BIOPHARMA, INC. (US) 2008-07-10 — — WO disclosed
CN-1883585-A Pharmaceutical composition for treating atherosclerosis and method for preparing same JIANGSU KANION PHARMACEUTICAL (CN) 2006-12-27 — — CN disclosed
EP-1088094-A1 BIOCATALYTIC PROCESS FOR THE PREPARATION OF 3-0-ACYL-FLAVONOIDS CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 2001-04-04 — — EP disclosed
WO-1999066062-A1 BIOCATALYTIC PROCESS FOR THE PREPARATION OF 3-0-ACYL-FLAVONOIDS CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1999-12-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090325906-A1 Methods and compositions for therapeutic treatment SLC2A1, SLC2A2, SLC2A3 MEN1 4409/4885KMT2A 4599/4885CYP1A2 3381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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