Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11846250 | 1.00 | AKR1B1 (0.55) | AKR1B1MAPK14DGKAELANEAPP | |
| SCHEMBL11839180 | 1.00 | AKR1B1 (0.55) | AKR1B1MAPK14DGKAELANEAPP | |
| SCHEMBL11853431 | 0.99 | AKR1B1 (0.56) | AKR1B1MAPK14DGKAELANEAPP | |
| SCHEMBL11850825 | 0.92 | AKR1B1 (0.59) | AKR1B1MAPK14APP | |
| SCHEMBL11570278 | 0.87 | AKR1B1 (0.64) | AKR1B1MAPK14ELANEEPHX2LMNA | |
| SCHEMBL11827878 | 0.87 | AKR1B1 (0.64) | AKR1B1MAPK14ELANEEPHX2LMNA | |
| SCHEMBL11570176 | 0.87 | AKR1B1 (0.64) | AKR1B1MAPK14ELANEEPHX2LMNA | |
| SCHEMBL11824625 | 0.87 | AKR1B1 (0.64) | AKR1B1MAPK14ELANEEPHX2LMNA | |
| SCHEMBL11845419 | 0.85 | AKR1B1 (0.55) | AKR1B1MAPK14ELANELMNAACHE | |
| SCHEMBL11851420 | 0.84 | AKR1B1 (0.64) | AKR1B1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3989839-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | SYNTEX (U.S.A.) INC. (US) | 1976-11-02 | — | — | US | disclosed |