SCHEMBL11845142

SCHEMBL11845142

CC1CC(Br)C(=O)CC1(C)C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3536966 0.69 KDM1A (0.42)
SCHEMBL2692336 0.66
SCHEMBL15307836 0.65 CRBN (0.30)
SCHEMBL9290687 0.65
SCHEMBL22902078 0.64 KDM4E (0.33) MAPT
SCHEMBL22901958 0.64 KDM4E (0.33) MAPT
SCHEMBL3536541 0.62 MAPT (0.41) MAPT
SCHEMBL24898762 0.62 TSHR (0.39) MAPT
SCHEMBL13196610 0.62
SCHEMBL7751251 0.62 TSHR (0.39) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3954984-A ANTISECRETRETORY AGENTS, CENTRAL NERVOUS SYSTEM DEPRESSANTS RICHARDSON-MERRELL INC. (US) 1976-05-04 US disclosed