Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 1.00 |
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.52 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.52 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11850062 | 0.93 | TSHR (0.86) | TSHRHTTGAAGFERCES2 | |
| SCHEMBL2493279 | 0.91 | TSHR (0.83) | TSHRHTTGAAGFERCES1 | |
| SCHEMBL11847278 | 0.89 | TSHR (0.80) | TSHRHTTGAAGFERKMT2A | |
| SCHEMBL11842852 | 0.89 | TSHR (0.80) | TSHRHTTGAAGFERKMT2A | |
| Hydrochloric Acid SCHEMBL11845788 | 0.88 | TSHR (0.78) | TSHRHTTGAAGFERKMT2A | |
| SCHEMBL11855278 | 0.86 | TSHR (0.75) | TSHRHTTGAAGFERCES2 | |
| SCHEMBL11850001 | 0.85 | TSHR (0.74) | TSHRHTTGAAGFERKMT2A | |
| Hydrochloric Acid SCHEMBL11851095 | 0.85 | TSHR (0.73) | TSHRHTTGAAGFERKMT2A | |
| SCHEMBL11849241 | 0.84 | TSHR (0.72) | TSHRHTTGAAGFERKMT2A | |
| SCHEMBL11838764 | 0.84 | TSHR (0.72) | TSHRHTTGAAGFERKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969506-A | BRONCHODILATOR | SANDOZ, INC. (US) | 1976-07-13 | — | — | US | claimed |
| US-3969506-A | BRONCHODILATOR | SANDOZ, INC. (US) | 1976-07-13 | — | — | US | disclosed |