Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11842297 | 0.88 | TSHR (0.45) | KDM4ETSHRCHRM2CHRM1CHRM3 | |
| SCHEMBL11846912 | 0.86 | TSHR (0.44) | KDM4ETSHRCHRM2CHRM1CHRM3 | |
| SCHEMBL11850013 | 0.85 | CHRM2 (0.46) | KDM4ETSHRCHRM2CHRM1CHRM3 | |
| SCHEMBL11855903 | 0.79 | KDM4E (0.43) | KDM4ETSHRCHRM2CHRM1CHRM3 | |
| SCHEMBL11846257 | 0.79 | TSHR (0.46) | KDM4ETSHRCHRM2CHRM1CHRM3 | |
| Sulfuric Acid SCHEMBL11852585 | 0.78 | TSHR (0.41) | KDM4ETSHRCHRM2CHRM1CHRM3 | |
| SCHEMBL11851912 | 0.77 | TSHR (0.42) | KDM4ETSHRMEN1KMT2AUSP2 | |
| SCHEMBL11847979 | 0.75 | TSHR (0.40) | KDM4ETSHRCHRM2CHRM1CHRM3 | |
| SCHEMBL11838006 | 0.73 | MAPT (0.39) | KDM4ETSHRCHRM2CHRM1CHRM3 | |
| SCHEMBL11841086 | 0.73 | USP2 (0.39) | KDM4ETSHRCHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3980788-A | XANTHENYL COMPOUNDS | SMITHKLINE CORPORATION (US) | 1976-09-14 | — | — | US | disclosed |