Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11846414 | 0.91 | AKR1B1 (0.54) | AKR1B1MAPK14MAPTTP53HTT | |
| SCHEMBL11848624 | 0.89 | AKR1B1 (0.52) | AKR1B1MAPK14MAPTTP53HTT | |
| SCHEMBL11843457 | 0.87 | AKR1B1 (0.50) | AKR1B1MAPK14MAPTTP53HTT | |
| SCHEMBL11848961 | 0.85 | AKR1B1 (0.47) | AKR1B1MAPK14MAPTKDM4ELMNA | |
| SCHEMBL11848142 | 0.84 | AKR1B1 (0.50) | AKR1B1MAPK14MAPTTP53HTT | |
| SCHEMBL11844096 | 0.84 | AKR1B1 (0.47) | AKR1B1MAPK14MAPTKDM4ELMNA | |
| SCHEMBL11851958 | 0.84 | AKR1B1 (0.47) | AKR1B1MAPK14MAPTKDM4ELMNA | |
| SCHEMBL11838664 | 0.84 | AKR1B1 (0.47) | AKR1B1MAPK14MAPTKDM4ELMNA | |
| SCHEMBL11840294 | 0.83 | AKR1B1 (0.57) | AKR1B1MAPK14MAPTTP53HTT | |
| SCHEMBL11850633 | 0.82 | AKR1B1 (0.48) | AKR1B1MAPK14MAPTTP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3989839-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | SYNTEX (U.S.A.) INC. (US) | 1976-11-02 | — | — | US | disclosed |