Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 14/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.64 |
| ▸ | MAPT | P10636 | 11/20 | 0.64 |
| ▸ | USP2 | O75604 | 5/20 | 0.64 |
| ▸ | CRHBP | P24387 | 3/20 | 0.64 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.64 |
| ▸ | IDE | P14735 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11854170 | 0.91 | MEN1 (0.57) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL11854175 | 0.91 | MEN1 (0.57) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL12424112 | 0.83 | MAPT (0.46) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL11315442 | 0.82 | MEN1 (0.45) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL13445167 | 0.82 | MAPT (0.45) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL13889560 | 0.82 | MAPT (0.52) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL10036074 | 0.81 | MAPT (0.61) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL24390185 | 0.80 | MAPT (0.70) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL14437580 | 0.79 | MEN1 (0.61) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL7697693 | 0.79 | MEN1 (0.62) | MEN1KMT2AMAPTUSP2CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3958991-A | PHOTOCONDUCTOR | EASTMAN KODAK COMPANY (US) | 1976-05-25 | — | — | US | claimed |