Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.34 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11848574 | 0.92 | HTT (0.38) | NAMPTHTTEGLN1CYP11B1CYP11B2 | |
| SCHEMBL6936226 | 0.82 | METAP1 (0.40) | HTT | |
| SCHEMBL11663442 | 0.77 | FFAR1 (0.40) | NAMPTDRD2 | |
| SCHEMBL6938641 | 0.76 | HSP90AB1 (0.41) | — | |
| SCHEMBL6931403 | 0.75 | HPGD (0.34) | HTTHDAC1MAOAMAOB | |
| SCHEMBL6933096 | 0.75 | METAP1 (0.44) | — | |
| SCHEMBL7789904 | 0.75 | PPARG (0.35) | HTT | |
| SCHEMBL6936638 | 0.74 | HSP90AB1 (0.36) | HTTNLRP3 | |
| SCHEMBL4839414 | 0.71 | HTT (0.44) | HTTEGLN1EGLN2 | |
| SCHEMBL30088460 | 0.71 | HTT (0.44) | HTTEGLN1EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3956363-A | Substituted indenyl acetic acids | MERCK & CO., INC. (US) | 1976-05-11 | — | — | US | disclosed |