Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 18/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 15/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 14/20 | 0.55 |
| ▸ | MTOR | P42345 | 9/20 | 0.53 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.48 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11849194 | 0.94 | PIK3CA (0.53) | PIK3CAPIK3CDPIK3CGMTORPIK3R1 | |
| Hydrochloric Acid SCHEMBL11851136 | 0.93 | PIK3CA (0.53) | PIK3CAPIK3CDPIK3CGMTORPIK3R1 | |
| SCHEMBL11857793 | 0.87 | PIK3CA (0.50) | PIK3CAPIK3CDPIK3CGMTORPIK3R1 | |
| SCHEMBL11852761 | 0.83 | SLC29A1 (0.41) | PIK3CAPIK3CDPIK3CGMTORPIK3R1 | |
| Hydrochloric Acid SCHEMBL11853330 | 0.82 | SLC29A1 (0.40) | PIK3CAPIK3CDPIK3CGMTORPIK3R1 | |
| SCHEMBL11045336 | 0.76 | SLC29A1 (0.47) | PIK3CASLC29A1 | |
| SCHEMBL11046569 | 0.76 | TSHR (0.49) | SLC29A1 | |
| Hydrochloric Acid SCHEMBL11851126 | 0.75 | PIK3CA (0.53) | PIK3CAPIK3CDPIK3CGMTORPIK3R1 | |
| SCHEMBL2276716 | 0.72 | PIK3CA (0.62) | PIK3CAPIK3CDPIK3CGMTORPIK3R1 | |
| SCHEMBL27272553 | 0.72 | PIK3CA (0.62) | PIK3CAPIK3CDPIK3CGMTORPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939268-A | 2,4-Diamino substituted pyridol(3,2-d)pyrimidine as antithrombotic agents | BOEHRINGER INGELHEIM GMBH (DT) | 1976-02-17 | — | — | US | disclosed |