Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.69 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.51 |
| ▸ | CDK2 | P24941 | 6/20 | 0.51 |
| ▸ | CCNA1 | P78396 | 6/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MARS1 | P56192 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11859557 | 0.95 | RAD52 (0.76) | RAD52CCNA2CDK2CCNA1F10 | |
| SCHEMBL11864104 | 0.91 | RAD52 (0.57) | RAD52CCNA2CDK2CCNA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11864998 | 0.90 | RAD52 (0.57) | RAD52CCNA2CDK2CCNA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11861513 | 0.90 | RAD52 (0.57) | RAD52CCNA2CDK2CCNA1ALDH1A1 | |
| SCHEMBL11856379 | 0.86 | RAD52 (0.90) | RAD52CCNA2CDK2CCNA1ALDH1A1 | |
| SCHEMBL11870590 | 0.85 | RAD52 (0.57) | RAD52CCNA2CDK2CCNA1F10 | |
| SCHEMBL11871559 | 0.85 | RAD52 (0.62) | RAD52CCNA2CDK2CCNA1ALDH1A1 | |
| SCHEMBL11865536 | 0.82 | RAD52 (0.61) | RAD52CCNA2CDK2CCNA1ALDH1A1 | |
| SCHEMBL32690250 | 0.81 | RAD52 (1.00) | RAD52CCNA2CDK2CCNA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11866779 | 0.81 | RAD52 (0.98) | RAD52CCNA2CDK2CCNA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000173-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-28 | — | — | US | disclosed |
| US-3940418-A | Esters and amides of 4,5-dihydrobenz[g]indazole-3-carboxylic acids and related compounds | G. D. SEARLE & CO. (US) | 1976-02-24 | — | — | US | disclosed |