Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.88 |
| ▸ | TTR | P02766 | 10/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.57 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.57 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.57 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11371017 | 0.94 | AKR1B1 (1.00) | AKR1B1TTRMEN1KMT2AALDH1A1 | |
| SCHEMBL11866919 | 0.89 | AKR1B1 (0.70) | AKR1B1TTRMEN1KMT2AALDH1A1 | |
| SCHEMBL11861511 | 0.88 | AKR1B1 (0.69) | AKR1B1TTRMEN1KMT2AALDH1A1 | |
| SCHEMBL11868129 | 0.87 | AKR1B1 (0.67) | AKR1B1TTRMEN1KMT2AALDH1A1 | |
| SCHEMBL11861274 | 0.87 | AKR1B1 (0.67) | AKR1B1TTRMEN1KMT2AALDH1A1 | |
| SCHEMBL11872502 | 0.86 | AKR1B1 (0.65) | AKR1B1TTRMEN1KMT2AALDH1A1 | |
| SCHEMBL11866371 | 0.85 | AKR1B1 (0.65) | AKR1B1TTRMEN1KMT2AALDH1A1 | |
| SCHEMBL11863812 | 0.85 | TTR (0.63) | AKR1B1TTRMEN1KMT2AALDH1A1 | |
| SCHEMBL11868923 | 0.85 | TTR (0.63) | AKR1B1TTRMEN1KMT2AALDH1A1 | |
| SCHEMBL11866390 | 0.84 | AKR1B1 (0.62) | AKR1B1TTRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3949084-A | Novel substituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-04-06 | — | — | US | disclosed |