Acetic Acid

Acetic Acid

SCHEMBL118599

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nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.89
CA4 P22748 3/20 0.58
LMNA P02545 2/20 0.50
TSHR P16473 2/20 0.46
THPO P40225 1/20 0.46
FFAR3 O14843 1/20 0.46
LCK P06239 1/20 0.46
FYN P06241 1/20 0.46
ALOX15 P16050 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
FAHD1 Q6P587 1/20 0.42
ALDH1A1 P00352 4/20 0.36
TDP1 Q9NUW8 1/20 0.36
KDM4E B2RXH2 1/20 0.36
CA2 P00918 1/20 0.36
PTGS1 P23219 1/20 0.36
MMP12 P39900 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL1880063 1.00 CA1 (0.89) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL1080 1.00
Acetic Acid SCHEMBL7101945 1.00
Acetic Acid SCHEMBL20272818 0.95 CA1 (0.80) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL4019924 0.95 CA1 (0.80) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL1367765 0.95 CA1 (0.80) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL8761316 0.95 CA1 (0.80) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL10797524 0.95 CA1 (0.80) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL10602749 0.95 CA1 (0.80) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL359080 0.95 CA1 (0.80) CA1CA4LMNATSHRTHPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107445194-A The preparation method of cerium dopping copper sulfide CdS quantum dots 吉林大学 2017-12-08 CN claimed
US-12134133-B2 Method to form copper nanoparticles UNIVERSITEIT GENT (BE) 2024-11-05 US disclosed
CN-117003773-A Preparation and application of copper urease acetate complex 合肥工业大学 2023-11-07 CN disclosed
US-20220388060-A1 A METHOD TO FORM COPPER NANOPARTICLES UNIVERSITEIT GENT (BE) 2022-12-08 US disclosed
EP-4061559-A1 A METHOD TO FORM COPPER NANOPARTICLES Universiteit Gent (BE) 2022-09-28 EP disclosed
WO-2021099486-A1 A METHOD TO FORM COPPER NANOPARTICLES UNIVERSITEIT GENT (BE) 2021-05-27 WO disclosed
CN-103180041-A Copper containing zsm-34, off and/or eri zeolitic material for selective reduction of nox BASF SE 2013-06-26 CN disclosed
CN-103167907-A For selective reduction of NOxCopper containing ZSM-34, OFF and/or ERI zeolitic materials BASF SE 2013-06-19 CN disclosed
CN-103118764-A Copper containing ZSM-34, OFF and /or ERI zeolitic material for selective reduction of NOx BASF SE 2013-05-22 CN disclosed
EP-2518537-A1 FILM MIRROR AND PROCESS FOR PRODUCTION THEREOF, AND REFLECTION DEVICE FOR GENERATION OF SOLAR POWER Konica Minolta Opto, Inc. (JP) 2012-10-31 EP disclosed
EP-2424362-A1 INSECTICIDE COMPOSITION COMPRISING A SPINOSYN, A METAL AND A PROTEINACEOUS MATERIAL Dow AgroSciences LLC (US) 2012-03-07 EP disclosed
EP-2424349-A1 PESTICIDE COMPOSITIONS EXHIBITING ENHANCED ACTIVITY AND METHODS FOR PREPARING SAME Dow AgroSciences LLC (US) 2012-03-07 EP disclosed
US-7145005-B2 2-(6-{2-[(2R)-2-Methyl-1-pyrrolidin-1-yl]-ethyl}-2-naphthalen-2-yl)-2H-pyridazin-3-one salts and their preparation ABBOTT LABORATORIES (US) 2006-12-05 US disclosed
US-20050256127-A1 2-(6-{2-[(2R)-2-methyl-1-pyrrolidin-1-yl]-ethyl}-2-naphthalen-2-yl)-2H-pyridazin-3-one salts and their preparation ABBVIE INC. 2005-11-17 US disclosed
EP-1263819-A1 METAL-FREE BINDERS FOR SELF-POLISHING ANTIFOULING PAINTS SIGMA COATINGS B.V. (NL) 2002-12-11 EP disclosed
WO-2001062811-A1 METAL-FREE BINDERS FOR SELF-POLISHING ANTIFOULING PAINTS SIGMA COATINGS B.V. (NL) 2001-08-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050256127-A1 2-(6-{2-[(2R)-2-methyl-1-pyrrolidin-1-yl]-ethyl}-2-naphthalen-2-yl)-2H-pyridazin-3-one salts and their preparation H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CYP2J2, NUP188 CA1 4832/4885CA4 4100/4885LMNA 578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.