Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11877197 | 0.93 | AOC3 (0.59) | AOC3PTGS1PTGS2SMN1; SMN2ATM | |
| SCHEMBL5490219 | 0.89 | AOC3 (0.54) | AOC3SMN1; SMN2CYP3A4CYP2D6HPGD | |
| SCHEMBL5491732 | 0.88 | AOC3 (0.65) | AOC3PTGS1PTGS2SMN1; SMN2ATM | |
| SCHEMBL22785949 | 0.84 | AOC3 (0.64) | AOC3PTGS1PTGS2ATMCYP3A4 | |
| SCHEMBL22785898 | 0.84 | AOC3 (0.64) | AOC3PTGS1PTGS2ATMCYP3A4 | |
| SCHEMBL19043557 | 0.82 | AOC3 (0.67) | AOC3PTGS1PTGS2CYP3A4CYP2D6 | |
| SCHEMBL14206671 | 0.82 | AOC3 (0.67) | AOC3PTGS1PTGS2CYP3A4CYP2D6 | |
| SCHEMBL16477749 | 0.81 | PTGS1 (0.53) | AOC3PTGS1PTGS2SMN1; SMN2ATM | |
| SCHEMBL17996460 | 0.81 | AOC3 (0.57) | AOC3PTGS1PTGS2SMN1; SMN2ATM | |
| SCHEMBL6321349 | 0.81 | AOC3 (0.61) | AOC3PTGS1PTGS2SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3946040-A | JUVENILE HORMONE ACTIVITY, INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1976-03-23 | — | — | US | disclosed |