Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5674453 | 0.84 | USP2 (0.46) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL1711900 | 0.84 | USP2 (0.46) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL1711904 | 0.84 | USP2 (0.46) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL1711899 | 0.84 | USP2 (0.46) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL7888124 | 0.82 | USP2 (0.45) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL7888410 | 0.82 | USP2 (0.45) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL1711635 | 0.82 | USP2 (0.45) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL7366756 | 0.82 | USP2 (0.45) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL1716534 | 0.82 | USP2 (0.45) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL7880579 | 0.82 | USP2 (0.45) | USP2SMN1; SMN2HPGDTP53ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101381350-B | Synthetic method of diethyl naphthylmethyl-tetrahydrofurfurylmalonate | ZHEJIANG TAIZHOU QINGQUAN MEDICAL & CHEMICAL CO LTD | 2011-06-29 | — | — | CN | claimed |
| CN-101381350-A | Synthetic method of diethyl naphthylmethyl-tetrahydrofurfurylmalonate | ZHEJIANG TAIZHOU QINGQUAN MEDI (CN) | 2009-03-11 | — | — | CN | claimed |
| CN-101381350-B | Synthetic method of diethyl naphthylmethyl-tetrahydrofurfurylmalonate | ZHEJIANG TAIZHOU QINGQUAN MEDICAL & CHEMICAL CO LTD | 2011-06-29 | — | — | CN | disclosed |
| CN-101381350-A | Synthetic method of diethyl naphthylmethyl-tetrahydrofurfurylmalonate | ZHEJIANG TAIZHOU QINGQUAN MEDI (CN) | 2009-03-11 | — | — | CN | disclosed |
| US-3973033-A | Compositions and methods for producing a vasodilatory effect with a naphthyl tetrahydrofurfuryl amino-ester | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1976-08-03 | — | — | US | disclosed |