Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.61 |
| ▸ | PPARD | Q03181 | 8/20 | 0.61 |
| ▸ | PPARA | Q07869 | 8/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | DNTT | P04053 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11866056 | 1.00 | PPARG (0.61) | PPARGPPARDPPARATRPA1NR4A2 | |
| SCHEMBL17451520 | 0.92 | PPARG (0.67) | PPARGPPARDPPARATRPA1NR4A2 | |
| SCHEMBL11800847 | 0.92 | PPARG (0.67) | PPARGPPARDPPARATRPA1NR4A2 | |
| SCHEMBL15287190 | 0.92 | PPARG (0.67) | PPARGPPARDPPARATRPA1NR4A2 | |
| SCHEMBL10018320 | 0.86 | PPARG (0.43) | PPARGPPARDPPARATRPA1NR4A2 | |
| SCHEMBL12034625 | 0.86 | PPARG (0.43) | PPARGPPARDPPARATRPA1NR4A2 | |
| SCHEMBL20792223 | 0.86 | PPARG (0.43) | PPARGPPARDPPARATRPA1NR4A2 | |
| SCHEMBL11866149 | 0.85 | PPARG (0.48) | PPARGPPARDPPARATRPA1NR4A2 | |
| SCHEMBL11866141 | 0.85 | PPARG (0.48) | PPARGPPARDPPARATRPA1NR4A2 | |
| SCHEMBL11866489 | 0.85 | DNTT (0.50) | PPARGPPARDPPARATRPA1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984455-A | Prostaglandin E1 analogs | THE UPJOHN COMPANY (US) | 1976-10-05 | — | — | US | disclosed |