⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51352 | 1.00 | — | — | |
| SCHEMBL4751122 | 1.00 | — | — | |
| SCHEMBL19665 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL5860643 | 0.87 | — | — | |
| SCHEMBL1952432 | 0.85 | — | — | |
| SCHEMBL5682973 | 0.82 | — | — | |
| Methylene Chloride SCHEMBL2347771 | 0.80 | — | — | |
| SCHEMBL4962709 | 0.78 | — | — | |
| SCHEMBL7339903 | 0.78 | — | — | |
| Phosphoric Acid SCHEMBL1936779 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9346816-B2 | 6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohept[f]indene derivatives, pharmaceutical compositions containing these compounds, their use and processes for preparing them | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-05-24 | — | — | US | disclosed |
| US-20140066428-A1 | 6,7,8,9-Tetrahydro-5H-1,4,7,10a-tetraaza-cyclohept[f]indene derivatives, pharmaceutical compositions containing these compounds, their use and processes for preparing them | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-03-06 | — | — | US | disclosed |
| US-20120165304-A1 | 6,7,8,9-Tetrahydro-5H-1,4,7,10a-tetraaza-cyclohept[f]indene derivatives, pharmaceutical compositions containing these compounds, their use and processes for preparing them | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-28 | — | — | US | disclosed |
| EP-2424888-A2 | INSULINOTROPIC PEPTIDE SYNTHESIS USING SOLID AND SOLUTION PHASE COMBINATION TECHNIQUES | F. Hoffmann-La Roche AG (CH) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010125079-A2 | INSULINOTROPIC PEPTIDE SYNTHESIS USING SOLID AND SOLUTION PHASE COMBINATION TECHNIQUES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-11-04 | — | — | WO | disclosed |
| EP-2222695-A2 | INSULINOTROPIC PEPTIDE SYNTHESIS USING SOLID AND SOLUTION PHASE COMBINATION TECHNIQUES | F. Hoffmann-La Roche AG (CH) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009074483-A2 | INSULINOTROPIC PEPTIDE SYNTHESIS USING SOLID AND SOLUTION PHASE COMBINATION TECHNIQUES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-06-18 | — | — | WO | disclosed |
| EP-1363878-B1 | PROCESS FOR PREPARING SULFAMOYL-SUBSTITUTED PHENETHYLAMINE DERIVATIVES | YONSUNG FINE CHEMICAL CO LTD (KR) | 2007-01-17 | — | — | EP | disclosed |
| EP-1363878-A4 | PROCESS FOR PREPARING SULFAMOYL-SUBSTITUTED PHENETHYLAMINE DERIVATIVES | YONSUNG FINE CHEMICAL CO LTD (KR) | 2005-12-21 | — | — | EP | disclosed |
| EP-1363878-A1 | PROCESS FOR PREPARING SULFAMOYL-SUBSTITUTED PHENETHYLAMINE DERIVATIVES | Yonsung Fine Chemical Co. Ltd (KR) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002068382-A1 | PROCESS FOR PREPARING SULFAMOYL-SUBSTITUTED PHENETHYLAMINE DERIVATIVES | YONSUNG FINE CHEMICAL CO. LTD. (KR) | 2002-09-06 | — | — | WO | disclosed |