Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.63 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.63 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | TTR | P02766 | 11/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11868304 | 0.87 | KDM4E (0.69) | KDM4EMEN1ALDH1A1TP53CYP2C9 | |
| SCHEMBL11322640 | 0.84 | TTR (0.80) | KDM4EMEN1ALDH1A1TP53CYP2C9 | |
| SCHEMBL11864035 | 0.82 | TTR (0.65) | KDM4EMEN1ALDH1A1TP53CYP2C9 | |
| SCHEMBL11874006 | 0.82 | KDM4E (0.65) | KDM4EMEN1ALDH1A1TP53CYP2C9 | |
| SCHEMBL11863211 | 0.82 | TTR (0.69) | KDM4EMEN1ALDH1A1TP53CYP2C9 | |
| SCHEMBL11865282 | 0.81 | CYP2C9 (0.65) | KDM4EMEN1ALDH1A1TP53CYP2C9 | |
| SCHEMBL11868149 | 0.81 | TTR (0.64) | KDM4EMEN1ALDH1A1TP53CYP2C9 | |
| SCHEMBL11858170 | 0.81 | KDM4E (0.60) | KDM4EMEN1ALDH1A1TP53CYP2C9 | |
| SCHEMBL11857659 | 0.80 | NPC1 (0.71) | KDM4EMEN1ALDH1A1TP53CYP2C9 | |
| SCHEMBL11871622 | 0.80 | KDM4E (0.60) | KDM4EMEN1ALDH1A1TP53CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3949084-A | Novel substituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-04-06 | — | — | US | disclosed |