Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23668736 | 0.97 | TSHR (0.64) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL9329297 | 0.97 | TSHR (0.69) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL27438198 | 0.95 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL28311362 | 0.95 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL4623822 | 0.92 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL28671372 | 0.92 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL11033659 | 0.92 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL19639290 | 0.91 | TSHR (0.65) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL5578122 | 0.90 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL11873914 | 0.90 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3965063-A | HYDROXYETHYL METHACRYLATE-N-(1,1-DIMETHYL-3-OXOBUTYL)ACRYLAMIDE, TRIMETHYLOLPROPANE TRIMETHACRYLATE | BURTON, PARSONS AND COMPANY, INC. (US) | 1976-06-22 | — | — | US | disclosed |