Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11869444 | 1.00 | TRPV1 (0.53) | TRPV1PPARGCNR1FFAR1PPARD | |
| SCHEMBL23490678 | 0.83 | CNR1 (0.55) | TRPV1PPARGCNR1FFAR1PPARD | |
| SCHEMBL19040782 | 0.83 | TRPV1 (0.53) | TRPV1PPARGFFAR1PPARDPPARA | |
| SCHEMBL28289999 | 0.83 | CNR1 (0.55) | TRPV1PPARGCNR1FFAR1PPARD | |
| SCHEMBL24719582 | 0.83 | TRPV1 (0.53) | TRPV1PPARGFFAR1PPARDPPARA | |
| SCHEMBL31259026 | 0.83 | CNR1 (0.55) | TRPV1PPARGCNR1FFAR1PPARD | |
| SCHEMBL28290001 | 0.83 | CNR1 (0.55) | TRPV1PPARGCNR1FFAR1PPARD | |
| SCHEMBL15508739 | 0.82 | — | — | |
| SCHEMBL19572670 | 0.82 | TRPV1 (0.73) | TRPV1PPARGCNR1FFAR1PPARD | |
| SCHEMBL3682342 | 0.82 | TRPV1 (0.73) | TRPV1PPARGCNR1FFAR1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953499-A | 8,12-Dialkyl-PGE, and PGF1.sub.α | THE UPJOHN COMPANY (US) | 1976-04-27 | — | — | US | disclosed |