Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.40 |
| ▸ | HTT | P42858 | 8/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | JAK2 | O60674 | 3/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11860841 | 0.86 | MAPT (0.38) | MAPTHTTPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL11868445 | 0.84 | MAPT (0.42) | MAPTHTTPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL31144987 | 0.77 | MAPT (0.41) | MAPTHTTPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL11867488 | 0.77 | KMT2A (0.34) | MAPTHTTPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL11867402 | 0.77 | MAPT (0.43) | MAPTHTTPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL8340603 | 0.76 | MAPT (0.50) | MAPTHTTPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL10102781 | 0.72 | MAPT (0.39) | MAPTHTTPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL10102725 | 0.71 | GAA (0.34) | MAPTHTTPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL11860831 | 0.70 | MAPT (0.36) | MAPTHTTPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL10102752 | 0.68 | KMT2A (0.33) | MAPTHTTPOLBNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3968228-A | 4-Nitro-5-cyanoimidazoles as coccidiostats | MERCK & CO., INC. (US) | 1976-07-06 | — | — | US | disclosed |