Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL318066 | 0.98 | MAPK1 (0.56) | MAPK1DDB1CRBNNPSR1TSHR | |
| SCHEMBL15874734 | 0.98 | MAPK1 (0.56) | MAPK1DDB1CRBNNPSR1TSHR | |
| SCHEMBL11637205 | 0.93 | DDB1 (0.55) | MAPK1DDB1CRBNALDH1A1KMT2A | |
| SCHEMBL4128714 | 0.81 | DDB1 (0.57) | MAPK1DDB1CRBNKMT2ACYP19A1 | |
| SCHEMBL318339 | 0.81 | MAPK1 (0.45) | MAPK1DDB1CRBNTSHRALDH1A1 | |
| SCHEMBL10109186 | 0.81 | MAPK1 (0.45) | MAPK1DDB1CRBNTSHRALDH1A1 | |
| SCHEMBL182434 | 0.80 | DDB1 (0.58) | MAPK1DDB1CRBNKMT2ACYP19A1 | |
| SCHEMBL4129415 | 0.80 | PDE4A (0.50) | MAPK1NPSR1ALDH1A1KMT2ARAB9A | |
| SCHEMBL1138156 | 0.79 | NPC1 (0.45) | ALDH1A1KMT2ACYP19A1NPC1RAB9A | |
| SCHEMBL11844345 | 0.78 | PDE4A (0.51) | MAPK1NPSR1ALDH1A1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3997557-A | ANTIARRHYTHMIA, CNS DEPRESSANT, ANTIINFLAMMATORY, HYPOTENSIVE | AMERICAN HOECHST CORPORATION (US) | 1976-12-14 | — | — | US | disclosed |