Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 11/20 | 0.54 |
| ▸ | TEK | Q02763 | 10/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14375377 | 0.90 | MEN1 (0.51) | KDRTEKMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31154057 | 0.88 | MEN1 (0.54) | KDRMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL5347951 | 0.85 | KDR (0.57) | KDRTEKMEN1KMT2ANPC1 | |
| SCHEMBL11875471 | 0.85 | KDR (0.69) | KDRTEKMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6398508 | 0.85 | KDR (0.45) | KDRTEKMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5346740 | 0.85 | TEK (0.68) | KDRTEKMEN1KMT2AMAPT | |
| SCHEMBL11879872 | 0.84 | KDR (0.60) | KDRTEKSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL11864339 | 0.84 | KDR (0.58) | KDRTEKSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL11878978 | 0.84 | KDR (0.61) | KDRTEKLMNAMAPK1HIF1A | |
| SCHEMBL29569399 | 0.84 | KDR (0.61) | KDRTEKLMNAMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3965113-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1976-06-22 | — | — | US | claimed |
| US-3965113-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1976-06-22 | — | — | US | disclosed |