Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.60 |
| ▸ | STAT1 | P42224 | 1/20 | 0.60 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 4/20 | 0.38 |
| ▸ | CYCS | P99999 | 3/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1650933 | 0.87 | STAT3 (0.60) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL30205816 | 0.83 | STAT3 (0.64) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL5015307 | 0.83 | STAT3 (0.64) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL7259660 | 0.83 | STAT3 (0.64) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL5319095 | 0.83 | STAT3 (0.64) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL7258061 | 0.83 | STAT3 (0.64) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL3352961 | 0.83 | STAT3 (0.64) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL29403134 | 0.83 | STAT3 (0.64) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL473158 | 0.82 | STAT3 (0.86) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL30753635 | 0.82 | STAT3 (0.86) | STAT3STAT1TOP1CYCSENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3935031-A | PORPHYRIN COMPOUND | NEW ENGLAND INSTITUTE, INC. (US) | 1976-01-27 | — | — | US | disclosed |