⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17494156 | 0.81 | TSHR (0.44) | — | |
| SCHEMBL6682775 | 0.81 | TSHR (0.36) | — | |
| SCHEMBL1188517 | 0.81 | — | — | |
| SCHEMBL29715 | 0.81 | — | — | |
| SCHEMBL13799597 | 0.78 | — | — | |
| SCHEMBL2153458 | 0.78 | — | — | |
| SCHEMBL9578386 | 0.78 | — | — | |
| SCHEMBL10923089 | 0.78 | — | — | |
| SCHEMBL10786843 | 0.78 | — | — | |
| SCHEMBL8405269 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114409520-B | Method for preparing trimethylolpropane by hydrogenation with high condensation yield | 万华化学集团股份有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-109825538-B | Synthesis method of chiral 2-amino-1-butanol | 中国科学院天津工业生物技术研究所 | 2022-05-24 | — | — | CN | claimed |
| CN-114409520-A | Method for preparing trimethylolpropane by hydrogenation with high condensation yield | 万华化学集团股份有限公司 | 2022-04-29 | — | — | CN | claimed |
| CN-110002982-A | The method for preparing polyalcohol | 伊斯曼化学公司 | 2019-07-12 | — | — | CN | claimed |
| EP-2951141-B1 | PROCESS FOR PRODUCING POLYOLS | EASTMAN CHEM CO (US) | 2019-06-19 | — | — | EP | claimed |
| CN-109825538-A | A kind of synthetic method of Chiral 2-amino-1-butanol | 中国科学院天津工业生物技术研究所 | 2019-05-31 | — | — | CN | claimed |
| CN-105073702-B | The preparation of hydroxy aldehyde | 伊斯曼化学公司 | 2017-11-24 | — | — | CN | claimed |
| EP-2951144-B1 | PREPARATION OF HYDROXY ALDEHYDES | EASTMAN CHEM CO (US) | 2017-07-05 | — | — | EP | claimed |
| CN-103881050-B | A kind of preparation method of light polyisocyanate curing agent | WANHUA CHEMICAL GROUP CO., LTD. (CN) | 2016-02-24 | — | — | CN | claimed |
| US-20150368171-A1 | PROCESS FOR PRODUCING POLYOLS | EASTMAN CHEMICAL COMPANY (US) | 2015-12-24 | — | — | US | claimed |
| US-9056824-B2 | Preparation of hydroxy aldehydes | EASTMAN CHEMICAL COMPANY (US) | 2015-06-16 | — | — | US | claimed |
| WO-2014120481-A1 | PROCESS FOR PRODUCING POLYOLS | EASTMAN CHEMICAL COMPANY (US) | 2014-08-07 | — | — | WO | claimed |
| WO-2014120480-A1 | PREPARATION OF HYDROXY ALDEHYDES | EASTMAN CHEMICAL COMPANY (US) | 2014-08-07 | — | — | WO | claimed |
| US-20140213827-A1 | PREPARATION OF HYDROXY ALDEHYDES | EASTMAN CHEMICAL COMPANY (US) | 2014-07-31 | — | — | US | claimed |
| CN-103881050-A | Preparation method of light-colored polyisocyanate curing agent | WANHUA CHEMICAL GROUP CO LTD | 2014-06-25 | — | — | CN | claimed |
| US-8710278-B1 | Process for producing polyols | EASTMAN CHEMICAL COMPANY (US) | 2014-04-29 | — | — | US | claimed |
| CN-102408304-B | Method for preparing alcohols by selectively hydrogenating aldehydes | CHINA PETROLEUM & CHEMICAL | 2014-04-02 | — | — | CN | claimed |
| CN-102408304-A | Method for preparing alcohols by selectively hydrogenating aldehydes | CHINA PETROLEUM & CHEMICAL | 2012-04-11 | — | — | CN | claimed |
| US-20070272852-A1 | Differential mobility spectrometer analyzer and pre-filter apparatus, methods, and systems | SIONEX CORPORATION (US) | 2007-11-29 | — | — | US | claimed |
| WO-2007120373-A2 | DIFFERENTIAL MOBILITY SPECTROMETER ANALYZER AND PRE-FILTER APPARATUS, METHODS AND SYSTEMS | SIONEX CORPORATION (US) | 2007-10-25 | — | — | WO | claimed |