⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13967075 | 0.86 | — | — | |
| SCHEMBL21964325 | 0.81 | — | — | |
| SCHEMBL1380121 | 0.81 | — | — | |
| SCHEMBL19400484 | 0.81 | — | — | |
| SCHEMBL12235285 | 0.77 | TP53 (0.33) | — | |
| SCHEMBL2194818 | 0.73 | KMT2A (0.48) | — | |
| SCHEMBL1269600 | 0.69 | TSHR (0.36) | — | |
| SCHEMBL13967466 | 0.69 | — | — | |
| SCHEMBL11549100 | 0.69 | — | — | |
| SCHEMBL107487 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2082005-B1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | PLEOTINT LLC (US) | 2012-08-01 | — | — | EP | claimed |
| US-20230213863-A1 | COMPOUND, RESIST UNDERLAYER FILM COMPOSITION INCLUDING SAME, AND RESIST UNDERLAYER FILM | DONGJIN SEMICHEM CO., LTD. (KR) | 2023-07-06 | — | — | US | disclosed |
| WO-2023086539-A2 | BCAT2 INHIBITORS | AGIOS PHARMACEUTICALS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| US-9943603-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-20150105553-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-04-16 | — | — | US | disclosed |
| US-8853185-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2014-10-07 | — | — | US | disclosed |
| US-20110263688-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | PURDUE RESEARCH FOUNDATION (US) | 2011-10-27 | — | — | US | disclosed |
| WO-2009126290-A2 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2009-10-15 | — | — | WO | disclosed |