Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 11/20 | 0.57 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.57 |
| ▸ | OXTR | P30559 | 9/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11889983 | 1.00 | AVPR2 (0.57) | AVPR2AVPR1AKCNH2OXTR | |
| SCHEMBL11889982 | 1.00 | AVPR2 (0.57) | AVPR2AVPR1AKCNH2OXTR | |
| SCHEMBL3320093 | 0.94 | AVPR1A (0.61) | AVPR2AVPR1AKCNH2OXTR | |
| SCHEMBL11890137 | 0.92 | AVPR2 (0.54) | AVPR2AVPR1AKCNH2OXTR | |
| SCHEMBL11890073 | 0.91 | AVPR2 (0.54) | AVPR2AVPR1AKCNH2OXTR | |
| SCHEMBL11890074 | 0.91 | AVPR2 (0.54) | AVPR2AVPR1AKCNH2OXTR | |
| SCHEMBL11889999 | 0.91 | AVPR2 (0.54) | AVPR2AVPR1AKCNH2OXTR | |
| SCHEMBL11889998 | 0.91 | AVPR2 (0.54) | AVPR2AVPR1AKCNH2OXTR | |
| SCHEMBL3321552 | 0.90 | AVPR2 (0.53) | AVPR2AVPR1AKCNH2OXTR | |
| SCHEMBL11890069 | 0.90 | AVPR2 (0.53) | AVPR2AVPR1AKCNH2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358714-B1 | ALKYLCYCLOHEXYLETHERS OF DIHYDROTETRAAZABENZOAZULENES | HOFFMANN LA ROCHE (CH) | 2012-08-01 | — | — | EP | claimed |