Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 20/20 | 0.66 |
| ▸ | MC5R | P33032 | 3/20 | 0.50 |
| ▸ | MC3R | P41968 | 3/20 | 0.50 |
| ▸ | MC1R | Q01726 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11891336 | 0.91 | MC4R (0.59) | MC4RMC5RMC3RMC1R | |
| SCHEMBL11891230 | 0.91 | MC4R (0.81) | MC4RMC5RMC3RMC1R | |
| SCHEMBL11891318 | 0.90 | MC4R (0.79) | MC4RMC5RMC3RMC1R | |
| SCHEMBL11891169 | 0.89 | MC4R (0.81) | MC4RMC5RMC3RMC1R | |
| SCHEMBL11891214 | 0.88 | MC4R (0.70) | MC4RMC5RMC3RMC1R | |
| SCHEMBL11891220 | 0.88 | MC4R (0.70) | MC4RMC5RMC3RMC1R | |
| SCHEMBL11891213 | 0.88 | MC4R (0.70) | MC4RMC5RMC3RMC1R | |
| SCHEMBL11891387 | 0.88 | MC4R (0.69) | MC4RMC5RMC3RMC1R | |
| SCHEMBL11891171 | 0.87 | MC4R (0.82) | MC4RMC5RMC3RMC1R | |
| SCHEMBL14226126 | 0.87 | MC4R (0.68) | MC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227485-B2 | Benzimidazole and imidazopyridine derivatives and use thereof as a medicament | IPSEN PHARMA S.A.S. (FR) | 2012-07-24 | — | — | US | disclosed |
| US-8227485-B2 | Benzimidazole and imidazopyridine derivatives and use thereof as a medicament | IPSEN PHARMA S.A.S. (FR) | 2012-07-24 | — | — | US | disclosed |
| EP-1692114-B1 | NOVEL BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AND USE THEREOF AS A MEDICAMENT | IPSEN PHARMA (FR) | 2010-09-22 | — | — | EP | disclosed |