Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 20/20 | 0.67 |
| ▸ | MC5R | P33032 | 3/20 | 0.67 |
| ▸ | MC3R | P41968 | 3/20 | 0.67 |
| ▸ | MC1R | Q01726 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11891366 | 0.96 | MC4R (0.68) | MC4RMC5RMC3RMC1R | |
| SCHEMBL11891126 | 0.92 | MC4R (0.74) | MC4RMC5RMC3RMC1R | |
| SCHEMBL11891359 | 0.86 | MC4R (0.76) | MC4RMC5RMC3RMC1R | |
| SCHEMBL11891135 | 0.86 | MC4R (0.64) | MC4RMC5RMC3RMC1R | |
| SCHEMBL11891143 | 0.86 | MC4R (0.75) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13124312 | 0.86 | MC4R (0.79) | MC4RMC5RMC3RMC1R | |
| SCHEMBL11891129 | 0.85 | MC4R (0.72) | MC4RMC5RMC3RMC1R | |
| SCHEMBL11891263 | 0.85 | MC4R (0.76) | MC4RMC5RMC3RMC1R | |
| SCHEMBL11891144 | 0.85 | MC4R (0.74) | MC4RMC5RMC3RMC1R | |
| SCHEMBL11891201 | 0.85 | MC4R (0.65) | MC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227485-B2 | Benzimidazole and imidazopyridine derivatives and use thereof as a medicament | IPSEN PHARMA S.A.S. (FR) | 2012-07-24 | — | — | US | disclosed |
| US-8227485-B2 | Benzimidazole and imidazopyridine derivatives and use thereof as a medicament | IPSEN PHARMA S.A.S. (FR) | 2012-07-24 | — | — | US | disclosed |
| EP-1692114-B1 | NOVEL BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AND USE THEREOF AS A MEDICAMENT | IPSEN PHARMA (FR) | 2010-09-22 | — | — | EP | disclosed |