Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 11/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.42 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11896361 | 0.93 | LPAR1 (0.53) | LPAR1LPAR3LPAR2SCN5ASCN9A | |
| SCHEMBL11895647 | 0.93 | LPAR1 (0.50) | LPAR1LPAR3LPAR2SCN5ASCN9A | |
| SCHEMBL11895986 | 0.89 | LPAR1 (0.53) | LPAR1LPAR3LPAR2SCN5ASCN9A | |
| SCHEMBL11895825 | 0.89 | LPAR1 (0.58) | LPAR1LPAR3LPAR2SCN5ASCN9A | |
| SCHEMBL11896247 | 0.87 | LPAR1 (0.46) | LPAR1LPAR3LPAR2SCN5ASCN9A | |
| SCHEMBL11896284 | 0.87 | LPAR1 (0.49) | LPAR1LPAR3LPAR2SCN5ASCN9A | |
| SCHEMBL3706566 | 0.87 | LPAR1 (0.62) | LPAR1LPAR3LPAR2CTSAPDE4B | |
| SCHEMBL4029085 | 0.86 | LPAR1 (0.58) | LPAR1LPAR3LPAR2SCN5ASCN9A | |
| SCHEMBL4028917 | 0.86 | LPAR1 (0.58) | LPAR1LPAR3LPAR2SCN5ASCN9A | |
| SCHEMBL11895259 | 0.85 | LPAR1 (0.47) | LPAR1LPAR3LPAR2SCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2462128-B1 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS INC (US) | 2016-09-21 | — | — | EP | claimed |
| US-8592402-B2 | Compounds as lysophosphatidic acid receptor antagonists | AMIRA PHARMACEUTICALS, INC. (US) | 2013-11-26 | — | — | US | claimed |
| US-20120196839-A1 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS INC. (US) | 2012-08-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196839-A1 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | LPAR1, LPAR2, LPAR4 | LPAR1 1/4885LPAR3 5/4885LPAR2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.