Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28943687 | 0.97 | PREP (0.51) | PREPOPRK1ALDH1A1GAA | |
| SCHEMBL1816285 | 0.97 | PREP (0.51) | PREPOPRK1ALDH1A1GAA | |
| SCHEMBL17293555 | 0.88 | PREP (0.49) | PREPOPRK1ALDH1A1 | |
| SCHEMBL1816147 | 0.88 | PREP (0.49) | PREPOPRK1ALDH1A1 | |
| SCHEMBL24555463 | 0.86 | PREP (0.48) | PREPOPRK1ALDH1A1 | |
| SCHEMBL22811016 | 0.83 | PREP (0.45) | PREPOPRK1ALDH1A1 | |
| SCHEMBL630719 | 0.82 | MEN1 (0.46) | FKBP1A | |
| SCHEMBL2084087 | 0.81 | PREP (0.49) | PREP | |
| SCHEMBL2084231 | 0.81 | PREP (0.48) | PREPOPRK1ALDH1A1 | |
| SCHEMBL22964984 | 0.79 | FOLH1 (0.51) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893056-B2 | Peptide deformylase inhibitors | GLAXOSMITHKLINE LLC (US) | 2011-02-22 | — | — | US | disclosed |