SCHEMBL1189751

SCHEMBL1189751

O=C1CCC=CCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9324253 0.85
SCHEMBL864016 0.81
SCHEMBL25497611 0.79
SCHEMBL5116662 0.79
SCHEMBL5116658 0.79
SCHEMBL23964332 0.75 OR51E2 (0.56)
SCHEMBL2920862 0.72
SCHEMBL13058104 0.70 GAA (0.48)
SCHEMBL26886694 0.70 OR51E2 (0.50)
SCHEMBL586833 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130045962-A1 PEPTIDE DEFORMYLASE INHIBITORS GLAXOSMITHKLINE LLC 2013-02-21 US claimed
US-20220219155-A1 Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2022-07-14 US disclosed
CN-111592492-A Method for improving quality of caprolactam product subjected to liquid phase Beckmann rearrangement 中国石油化工股份有限公司 2020-08-28 CN disclosed
US-20140323476-A1 PEPTIDE DEFORMYLASE INHIBITORS GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 2) LIMITED (GB) 2014-10-30 US disclosed
US-20130045962-A1 PEPTIDE DEFORMYLASE INHIBITORS GLAXOSMITHKLINE LLC 2013-02-21 US disclosed
WO-2013010676-A2 SUPPORTED IONIC LIQUID PHASE CATALYST ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES (FR) 2013-01-24 WO disclosed
US-7893056-B2 Peptide deformylase inhibitors GLAXOSMITHKLINE LLC (US) 2011-02-22 US disclosed
EP-1648865-B1 PROCESS FOR PURIFYING CAPROLACTAM DSM IP ASSETS BV (NL) 2010-04-21 EP disclosed
US-20090306066-A1 PEPTIDE DEFORMYLASE INHIBITORS GLAXOSMITHKLINE LLC 2009-12-10 US disclosed
US-20070060750-A1 Process for purifying caprolactam DSM IP ASSETS B.V. (NL) 2007-03-15 US disclosed
US-7001899-B2 Interleukin converting enzyme inhibitors THE PROCTER & GAMBLE COMPANY (US) 2006-02-21 US disclosed
US-20040009966-A1 7-member ring N-heterocycles that have a cysteine trap substitution; treating osteoarthritis THE PROCTER & GAMBLE COMPANY 2004-01-15 US disclosed
US-5326850-A Radiation crosslinking, high heat deflection temperature BASF AKTIENGESELLSCHAFT (DE) 1994-07-05 US disclosed
US-5266656-A Blends of polyamides and polyamides with olefin bonds BASF AKTIENGESELLSCHAFT (DE) 1993-11-30 US disclosed