Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.58 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | CPT2 | P23786 | 1/20 | 0.53 |
| ▸ | CPT1A | P50416 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25678350 | 1.00 | PREP (0.58) | PREPFKBP1ANPSR1CTSBCTSS | |
| SCHEMBL27848134 | 1.00 | PREP (0.58) | PREPFKBP1ANPSR1CTSBCTSS | |
| SCHEMBL10756725 | 0.96 | PREP (0.62) | PREPNPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL489615 | 0.96 | PREP (0.62) | PREPNPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL10756717 | 0.96 | PREP (0.62) | PREPNPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL4185467 | 0.91 | PREP (0.56) | PREPNPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL8604450 | 0.90 | PREP (0.58) | PREPFKBP1ANPSR1CTSBCTSS | |
| SCHEMBL13500680 | 0.86 | PREP (0.61) | PREPFKBP1ANPSR1CTSBCTSS | |
| SCHEMBL13119286 | 0.86 | PREP (0.61) | PREPFKBP1ANPSR1CTSBCTSS | |
| SCHEMBL14828710 | 0.86 | PREP (0.61) | PREPFKBP1ANPSR1CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101917981-B | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORP | 2012-11-14 | — | — | CN | disclosed |
| US-7893056-B2 | Peptide deformylase inhibitors | GLAXOSMITHKLINE LLC (US) | 2011-02-22 | — | — | US | disclosed |
| CN-101917981-A | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORP | 2010-12-15 | — | — | CN | disclosed |