Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 17/20 | 0.68 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.60 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.60 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.60 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.60 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.60 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.60 |
| ▸ | F2 | P00734 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3746654 | 0.99 | PSMB5 (0.67) | PSMB5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL30949851 | 0.89 | PSMB5 (0.70) | PSMB5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20400476 | 0.89 | PSMB5 (0.75) | PSMB5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20400473 | 0.89 | PSMB5 (0.75) | PSMB5PSEN1PSEN2APH1BNCSTN | |
| Hydrochloric Acid SCHEMBL21529940 | 0.88 | PSMB5 (0.73) | PSMB5PSEN1PSEN2APH1BNCSTN | |
| Hydrochloric Acid SCHEMBL21529938 | 0.88 | PSMB5 (0.73) | PSMB5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL30959043 | 0.88 | PSMB5 (0.79) | PSMB5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3748190 | 0.88 | PSMB5 (0.69) | PSMB5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3748186 | 0.88 | PSMB5 (0.69) | PSMB5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL22387868 | 0.87 | PSMB5 (0.70) | PSMB5PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212334-B1 | PROTEASOME INHIBITORS | MILLENNIUM PHARM INC (US) | 2012-08-15 | — | — | EP | disclosed |