Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 18/20 | 0.59 |
| ▸ | TDO2 | P48775 | 2/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11904140 | 0.86 | IDO1 (0.54) | IDO1TDO2IDO2APAF1 | |
| SCHEMBL11904139 | 0.86 | IDO1 (0.54) | IDO1TDO2IDO2APAF1 | |
| SCHEMBL4593270 | 0.84 | IDO1 (0.54) | IDO1TDO2 | |
| SCHEMBL6807657 | 0.84 | IDO1 (0.54) | IDO1TDO2 | |
| SCHEMBL6808994 | 0.82 | IDO1 (0.52) | IDO1TDO2IDO2 | |
| SCHEMBL14442332 | 0.75 | IDO1 (1.00) | IDO1TDO2IDO2APAF1 | |
| SCHEMBL4593735 | 0.74 | IDO1 (0.75) | IDO1TDO2IDO2APAF1 | |
| SCHEMBL4587505 | 0.74 | IDO1 (1.00) | IDO1TDO2IDO2APAF1 | |
| SCHEMBL4593677 | 0.74 | IDO1 (1.00) | IDO1TDO2IDO2APAF1 | |
| SCHEMBL4586115 | 0.74 | IDO1 (0.75) | IDO1TDO2IDO2APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594524-B1 | USE OF TRYPTANTHRIN COMPOUNDS FOR IMMUNE POTENTIATION | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2012-08-15 | — | — | EP | claimed |