⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21433566 | 1.00 | — | — | |
| SCHEMBL31274452 | 0.72 | — | — | |
| SCHEMBL5153034 | 0.72 | — | — | |
| SCHEMBL459324 | 0.69 | — | — | |
| SCHEMBL459323 | 0.69 | — | — | |
| SCHEMBL22112 | 0.67 | — | — | |
| SCHEMBL22111 | 0.67 | — | — | |
| SCHEMBL1760692 | 0.67 | — | — | |
| SCHEMBL781842 | 0.67 | — | — | |
| SCHEMBL2346382 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354926-A | Heterocyclic compounds as Pol theta inhibitors, process for their preparation and their use | 武汉人福创新药物研发中心有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-111542525-B | Selective inhibitors of protein arginine methyltransferase 5 (PRMT 5) | 普莱鲁德疗法有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-114249652-A | Phenol derivative and application thereof in medicine | 天地恒一制药股份有限公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-107068914-B | Hole transport compositions and related devices and methods (I) | 日产化学工业株式会社 | 2020-05-08 | — | — | CN | disclosed |
| EP-3548578-A1 | POLYMER FOR THERMAL INTERFACE WITH LOW THERMAL RESISTANCE AND THERMAL INTERFACE | Thales (FR) | 2019-10-09 | — | — | EP | disclosed |
| EP-2492262-B1 | FUSED HETEROCYCLIC COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | NISSAN CHEMICAL IND LTD (JP) | 2016-04-20 | — | — | EP | disclosed |
| US-8889732-B2 | Fused heterocyclic compounds and thrombopoietin receptor activators | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-11-18 | — | — | US | disclosed |
| EP-2492262-A1 | FUSED HETEROCYCLIC COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | Nissan Chemical Industries, Ltd. (JP) | 2012-08-29 | — | — | EP | disclosed |
| US-20120209005-A1 | FUSED HETEROCYCLIC COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-08-16 | — | — | US | disclosed |