Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 11/20 | 1.00 |
| ▸ | CA12 | O43570 | 10/20 | 1.00 |
| ▸ | CA1 | P00915 | 9/20 | 1.00 |
| ▸ | CA6 | P23280 | 5/20 | 1.00 |
| ▸ | CA7 | P43166 | 5/20 | 1.00 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 1.00 |
| ▸ | CA4 | P22748 | 5/20 | 1.00 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 1.00 |
| ▸ | CA5A | P35218 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CA2 | P00918 | 3/20 | 0.77 |
| ▸ | CA3 | P07451 | 3/20 | 0.77 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycoumarin SCHEMBL9751650 | 0.91 | CA9 (0.83) | CA9CA12CA1CA6CA7 | |
| SCHEMBL11036182 | 0.88 | CA9 (0.79) | CA9CA12CA1CA6CA7 | |
| SCHEMBL19194269 | 0.87 | CA12 (0.77) | CA9CA12CA1CA6CA7 | |
| 7-Propoxycoumarin SCHEMBL6690398 | 0.87 | CA9 (1.00) | CA9CA12CA1CA6CA7 | |
| 7-Butoxycoumarin SCHEMBL6686295 | 0.87 | CA12 (1.00) | CA9CA12CA1CA6CA7 | |
| SCHEMBL12304245 | 0.86 | CA12 (0.81) | CA9CA12CA1CA6CA7 | |
| SCHEMBL14329518 | 0.84 | CA12 (0.94) | CA9CA12CA1CA6CA7 | |
| SCHEMBL4390526 | 0.84 | CA12 (0.71) | CA9CA12CA1CA6CA7 | |
| SCHEMBL2984644 | 0.83 | CA12 (0.71) | CA9CA12CA1CA6CA7 | |
| SCHEMBL11457414 | 0.83 | CA12 (0.91) | CA9CA12CA1CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1527 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479259-B1 | Multi-cryopreserved hepatocytes and methods for their preparation | IN VITRO INC (US) | 2023-11-22 | — | — | EP | claimed |
| EP-3990654-B1 | MODIFIED MONOOXYGENASES FOR THE MANUFACTURE OF HYDROXYLATED AROMATIC HYDROCARBONS | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2023-10-04 | — | — | EP | claimed |
| CN-113979981-B | Sulfhydryl response type dealkalized site capture reagent and application | 天津医科大学 | 2023-04-07 | — | — | CN | claimed |
| CN-111218430-B | NADH analogue dependent cytochrome P450reductase and application thereof | 中国科学院大连化学物理研究所 | 2022-06-14 | — | — | CN | claimed |
| CN-113979981-A | Sulfhydryl response type dealkalized site capture reagent and application | 天津医科大学 | 2022-01-28 | — | — | CN | claimed |
| CN-111218430-A | NADH analogue dependent cytochrome P450reductase and application thereof | 中国科学院大连化学物理研究所 | 2020-06-02 | — | — | CN | claimed |
| US-9132115-B2 | Lipid raft, caveolin protein, and caveolar function modulation compounds and associated synthetic and therapeutic methods | KAY HEIDI (US) | 2015-09-15 | — | — | US | claimed |
| US-9127092-B2 | Method for producing polydienes and polydiene copolymers with reduced cold flow | BRIDGESTONE CORPORATION (JP) | 2015-09-08 | — | — | US | claimed |
| US-20140187725-A1 | METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2014-07-03 | — | — | US | claimed |
| EP-1200110-B1 | IN VIVO INDUCTION FOR ENHANCED FUNCTION OF ISOLATED HEPATOCYTES | ORGANOGENESIS INC (US) | 2014-04-23 | — | — | EP | claimed |
| US-6017760-A | AN ISOLATED POPULATION OF PRIMARY SWINE HEPATOCYTES ENRICHED FOR PERICENTRAL CELLS AND ARE HIGH IN ENZYME ACTIVITY FOR METABOLISM OF TOXIC COMPOUNDS; CULTURING CELLS TO PROLONG PROLIFERATION AND ENZYME ACTIVITY; THERAPY FOR LIVER FAILURE | RHODE ISLAND HOSPITAL (US) | 2000-01-25 | — | — | US | claimed |
| EP-0854912-A1 | ISOLATION AND CULTURE OF PORCINE HEPATOCYTES | RHODE ISLAND HOSPITAL (US) | 1998-07-29 | — | — | EP | claimed |
| US-5663029-A | DEVELOPMENT OF LATENT IMAGE, TRANSFERRING TO FORM RECORDING SHEETS, COATING A SUBSTRATE USING POLYMERS | XEROX CORPORATION (US) | 1997-09-02 | — | — | US | claimed |
| WO-1997013840-A1 | ISOLATION AND CULTURE OF PORCINE HEPATOCYTES | RHODE ISLAND HOSPITAL (US) | 1997-04-17 | — | — | WO | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| EP-0618972-A1 | CONSTITUTIVE EXPRESSION OF P450SOY AND FERREDOXIN-SOY IN $i(STREPTOMYCES), AND BIOTRANSFORMATION OF CHEMICALS BY RECOMBINANT ORGANISMS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-10-12 | — | — | EP | claimed |
| WO-1993012236-A1 | CONSTITUTIVE EXPRESSION OF P450SOY AND FERREDOXIN-SOY IN STREPTOMYCES, AND BIOTRANSFORMATION OF CHEMICALS BY RECOMBINANT ORGANISMS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-06-24 | — | — | WO | claimed |