Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 17/20 | 0.58 |
| ▸ | CNR1 | P21554 | 11/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11906692 | 1.00 | CNR2 (0.58) | CNR2CNR1TP53GFER | |
| SCHEMBL11906098 | 0.99 | CNR2 (0.56) | CNR2CNR1TP53GFER | |
| SCHEMBL11907678 | 0.86 | KMT2A (0.44) | CNR2CNR1TP53GFER | |
| SCHEMBL11907054 | 0.84 | CNR2 (0.53) | CNR2CNR1 | |
| SCHEMBL11907306 | 0.84 | CNR2 (0.53) | CNR2CNR1 | |
| SCHEMBL2745604 | 0.82 | CNR2 (0.66) | CNR2CNR1TP53 | |
| SCHEMBL2745557 | 0.82 | CNR2 (0.66) | CNR2CNR1TP53 | |
| SCHEMBL11907073 | 0.81 | MAPT (0.38) | CNR2CNR1GFER | |
| SCHEMBL2745682 | 0.81 | CNR2 (0.64) | CNR2CNR1TP53 | |
| SCHEMBL11907801 | 0.81 | GFER (0.38) | CNR2CNR1TP53GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20120208813-A1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVES | SHIONOGI & CO., LTD. | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208813-A1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVES | CNR2, CNR1, HRH4 | CNR2 1/4885CNR1 2/4885TP53 3391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.