⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1190830 | 1.00 | — | — | |
| SCHEMBL109550 | 0.83 | TSHR (0.33) | — | |
| SCHEMBL109549 | 0.83 | TSHR (0.33) | — | |
| SCHEMBL17764763 | 0.83 | TSHR (0.33) | — | |
| SCHEMBL4455007 | 0.78 | — | — | |
| SCHEMBL4455005 | 0.78 | — | — | |
| SCHEMBL2118191 | 0.77 | — | — | |
| SCHEMBL2118194 | 0.77 | — | — | |
| SCHEMBL2121145 | 0.75 | — | — | |
| SCHEMBL2121141 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7888338-B2 | 7-(2-cyclohexylidene-ethylidene)-spiro[4.5]decanes | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2011-02-15 | — | — | US | claimed |
| US-20060178350-A1 | 7-(2-Cyclohexylidene-ethylidene)-spiro[4.5]decanes | UNIVERSITEIT GENT (BE) | 2006-08-10 | — | — | US | claimed |
| WO-2006060884-A1 | 7-(2-CYCLOHEXYLIDENE-ETHYLIDENE)-SPIRO[4.5]DECANES | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2006-06-15 | — | — | WO | claimed |
| CN-118119588-A | Precursors for phenolic aromatic compounds | 奇华顿股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| US-20230250218-A1 | URETHANE COMPOSITION | NITTO KASEI CO., LTD. (JP) | 2023-08-10 | — | — | US | disclosed |
| EP-4198068-A1 | URETHANE COMPOSITION | Nitto Kasei Co., Ltd. (JP) | 2023-06-21 | — | — | EP | disclosed |
| WO-2023083576-A1 | PRECURSORS OF PHENOLIC FRAGRANT COMPOUNDS | GIVAUDAN SA (CH) | 2023-05-19 | — | — | WO | disclosed |
| WO-2023065200-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2023-04-27 | — | — | WO | disclosed |
| CN-116018365-A | Carbamate composition | 日东化成株式会社 | 2023-04-25 | — | — | CN | disclosed |
| EP-2444401-B1 | NOVEL IMIDAZOPYRIDINE COMPOUND | ONO PHARMACEUTICAL CO (JP) | 2014-09-03 | — | — | EP | disclosed |
| CN-101720317-B | Process for producing difluoromethyl-substituted pyrazole compound | BASF SE | 2014-07-09 | — | — | CN | disclosed |
| EP-0761225-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING PERIPHERAL CIRCULATION DISORDER | TEIJIN LIMITED (JP) | 1997-03-12 | — | — | EP | disclosed |
| US-5610182-A | ADMINISTERING AN ISOCARBACYCLIN OF SPECIFIC STRUCTURE IN THE FORM OF A FAT EMULSION | TEIJIN, LIMITED (JP) | 1997-03-11 | — | — | US | disclosed |
| US-5530027-A | PROSTAGLANDINS AND/OR ITS OPTICAL ISOMER FOR SKIN DISORDERS | TEIJIN LIMITED (JP) | 1996-06-25 | — | — | US | disclosed |
| CN-1102039-A | External skin therapeutic agent composition containing isocarbacyclin as active ingredient | TEIJIN LTD (JP) | 1995-04-26 | — | — | CN | disclosed |
| CN-1102038-A | External skin therapeutic agent composition containing prostacyclin as active ingredient | TEIJIN LTD (JP) | 1995-04-26 | — | — | CN | disclosed |
| CN-1101781-A | Pharmaceutical composition for treating cerebral thrombosis | TEIJIN LTD (JP) | 1995-04-19 | — | — | CN | disclosed |
| EP-0638312-A1 | DERMATOLOGIC PREPARATION COMPOSITION CONTAINING ISOCARBACYCLIN AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1995-02-15 | — | — | EP | disclosed |
| EP-0634172-A1 | DERMATOLOGIC PREPARATION COMPOSITION CONTAINING PROSTACYCLIN AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1995-01-18 | — | — | EP | disclosed |
| EP-0634171-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING CEREBRAL THROMBOSIS | TEIJIN LIMITED (JP) | 1995-01-18 | — | — | EP | disclosed |