Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.47 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL31626822 | 1.00 | CA4 (0.47) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL3215035 | 0.96 | CA4 (0.44) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL29237170 | 0.96 | CA4 (0.44) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL31753874 | 0.96 | — | — | |
| Glycine SCHEMBL15542463 | 0.96 | CA4 (0.44) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL2991904 | 0.96 | CA4 (0.44) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL29213859 | 0.96 | CA4 (0.44) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL2916896 | 0.96 | CA4 (0.50) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL2708039 | 0.92 | CA4 (0.47) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL7199765 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3110 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3612542-B1 | ENERGY-EFFICIENT SOLVENT-FREE METHOD FOR PRODUCING METAL CHELATES | TECHNISCHE UNIV CLAUSTHAL (DE) | 2026-04-22 | — | — | EP | claimed |
| US-12599138-B2 | Cellulosic fibers comprising internally dispersed cuprous oxide nanoparticles | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2026-04-14 | — | — | US | claimed |
| US-12582149-B1 | Functional additive for hot beverages and foods | MILJKOVIC IGOR (US) | 2026-03-24 | — | — | US | claimed |
| US-12479778-B2 | Plant food to enhance the nutritional value of pollen and nectar of plants to attract bees, butterflies and other pollinators | MAIWALD DIANE (US) | 2025-11-25 | — | — | US | claimed |
| US-20250302070-A1 | PROBIOTIC CAT FOOD FOR IMPROVING DIGESTIVE FUNCTION OF PET CAT AND PREPARATION METHOD THEREOF | Food Laboratory of Zhongyuan (CN) | 2025-10-02 | — | — | US | claimed |
| US-20250302037-A1 | MULTICOMPONENT FUNGICIDES | ADAMA MAKHTESHIM LTD. (IL) | 2025-10-02 | — | — | US | claimed |
| US-20250268950-A1 | PRENATAL SUPPLEMENT | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2025-08-28 | — | — | US | claimed |
| US-12398157-B2 | Energy-efficient solvent-free method for producing metal chelates | TECHNISCHE UNIVERSITAT CLAUSTHAL (DE) | 2025-08-26 | — | — | US | claimed |
| US-20250212881-A1 | AN AGROCHEMICAL COMPOSITION | UPL LTD (IN) | 2025-07-03 | — | — | US | claimed |
| CN-120189975-A | Preparation method and application of SAPO-34 composite material with Cu-Cu active site | 广东工业大学 | 2025-06-24 | — | — | CN | claimed |
| US-5006579-A | Halogen-containing resin composition | FERRO CORPORATION, A CORP. OF THE U.S.A. | 1991-04-09 | — | — | US | claimed |
| EP-0336982-A1 | HALOGENATED RESIN COMPOSITION | FERRO CORPORATION (US) | 1989-10-18 | — | — | EP | claimed |
| US-4824661-A | COPPER SALT, 2,4,4*-TRICHLORO-2*-HYDROXYDIPHENYL ETHER | BLENDAX-WERKE R. SCHNEIDER GMBH & CO. (DE) | 1989-04-25 | — | — | US | claimed |
| US-4479803-A | Agent for oxidative dyeing of hair | WELLA AKTIENGESELLSCHAFT (DE) | 1984-10-30 | — | — | US | claimed |
| US-4339429-A | Toothpaste active against plaque comprising a copper compound and a plastic polishing agent | BLENDAX-WERKE R. SCHNEIDER GMBH & CO. (DE) | 1982-07-13 | — | — | US | claimed |
| US-4332791-A | NONDISCOLORING | BLENDAX-WERKE R. SCHNEIDER GMBH & CO. (DE) | 1982-06-01 | — | — | US | claimed |
| US-4326523-A | CONTROLLED RELEASE PELLETS | INTERNATIONAL MINERALS & CHEMICAL CORP. (US) | 1982-04-27 | — | — | US | claimed |
| US-4270953-A | STORAGE STABILITY | KANSAI PAINT CO., LTD. (JP) | 1981-06-02 | — | — | US | claimed |
| US-4200337-A | Catalyses of uranium oxidation | WESTINGHOUSE ELECTRIC CORP. (US) | 1980-04-29 | — | — | US | claimed |
| US-4067890-A | Oxidative coupling of alkylphenols, alkoxyphenols and naphthols catalyzed by metal complexes of amino carboxylic and amino sulfonic acids | ICI AMERICA INC. (US) | 1978-01-10 | — | — | US | claimed |