Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.49 |
| ▸ | RAB9A | P51151 | 12/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11917669 | 0.91 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2HPGDNFKB1 | |
| SCHEMBL13901060 | 0.88 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2HPGDNFKB1 | |
| SCHEMBL11917685 | 0.84 | SMN1; SMN2 (0.41) | NPC1RAB9ASMN1; SMN2HPGDNFKB1 | |
| SCHEMBL12157455 | 0.81 | PDK2 (0.45) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL19726524 | 0.81 | PDK2 (0.45) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL12157449 | 0.81 | PDK2 (0.45) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL10013962 | 0.81 | PDK2 (0.45) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL14558242 | 0.81 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2HPGDNFKB1 | |
| SCHEMBL14465528 | 0.81 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2HPGDNFKB1 | |
| SCHEMBL11917694 | 0.81 | PDK2 (0.39) | NPC1RAB9AKMT2AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242235-B2 | Purification process of electroluminescent material, electroluminescent material and electroluminescent device | HITACHI CHEMICAL CO., LTD. (JP) | 2012-08-14 | — | — | US | disclosed |