SCHEMBL119203

SCHEMBL119203

Cc1cc(C#N)c(C)cc1C#N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
ALDH1A1 P00352 5/20 0.38
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
POLB P06746 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP2A6 P11509 1/20 0.35
KDM4E B2RXH2 3/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
APOBEC3G Q9HC16 1/20 0.34
HAVCR2 Q8TDQ0 1/20 0.34
AR P10275 4/20 0.33
S1PR1 P21453 1/20 0.33
CSNK1D P48730 1/20 0.33
CSNK1G2 P78368 1/20 0.33
USP2 O75604 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10098510 0.94 TSHR (0.46) TSHRALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL4203403 0.94 TSHR (0.46) TSHRALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL5945887 0.90 TSHR (0.48) TSHRALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL30394200 0.87 TSHR (0.50) TSHRALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL8954330 0.87 TSHR (0.50) TSHRALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL6322423 0.87 TSHR (0.41) TSHRALDH1A1KMT2AMEN1L3MBTL1
Bicarbonate SCHEMBL11599443 0.87 TSHR (0.41) TSHRALDH1A1KMT2AL3MBTL1POLB
SCHEMBL1343737 0.87 TSHR (0.41) TSHRALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL179206 0.85 TSHR (0.44) TSHRALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL7714672 0.84 KDM4E (0.48) TSHRALDH1A1KMT2AMEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250066528-A1 Method for Synthesizing a Covalent Organic Framework Material YOCOF MAT SUZHOU CO LTD (CN) 2025-02-27 US claimed
CN-114512719-B Eutectic solvent-based electrolyte and application thereof 中国科学院青岛生物能源与过程研究所 2024-12-03 CN claimed
CN-119039550-A Vinyl high-crystallinity covalent organic framework film, film sensor, preparation method and application thereof 南开大学 2024-11-29 CN claimed
CN-118526517-A Method for adsorbing enterogenic protein combined uremic toxin and precursor thereof 南开大学 2024-08-23 CN claimed
CN-114773556-B Green solid-phase synthesis method of covalent organic framework material 耀科新材料(苏州)有限公司 2024-06-04 CN claimed
WO-2023124952-A1 GREEN SOLID-PHASE SYNTHESIS METHOD FOR COVALENT ORGANIC FRAMEWORK MATERIAL 张振杰 2023-07-06 WO claimed
CN-114773556-A Green solid-phase synthesis method of covalent organic framework material 南开大学 2022-07-22 CN claimed
CN-114512719-A Eutectic solvent-based electrolyte and application thereof 中国科学院青岛生物能源与过程研究所 2022-05-17 CN claimed
US-4448940-A POLYOXAZOLINES BASED ON DINITRILES AND DIEPOXY COMPOUNDS; POLYISOCYANURATE; FLEXIBILITY; PRINTED CIRCUITS HITACHI, LTD. (JP) 1984-05-15 US claimed
CN-118994691-B Quantum dot/nano sheet doped coating reflecting film and preparation method thereof 宁波长阳科技股份有限公司 2025-04-01 CN disclosed
US-20250066528-A1 Method for Synthesizing a Covalent Organic Framework Material YOCOF MAT SUZHOU CO LTD (CN) 2025-02-27 US disclosed
CN-114512719-B Eutectic solvent-based electrolyte and application thereof 中国科学院青岛生物能源与过程研究所 2024-12-03 CN disclosed
CN-119039550-A Vinyl high-crystallinity covalent organic framework film, film sensor, preparation method and application thereof 南开大学 2024-11-29 CN disclosed
CN-118994691-A Quantum dot/nano sheet doped coating reflecting film and preparation method thereof 宁波长阳科技股份有限公司 2024-11-22 CN disclosed
EP-1073128-A2 Organic electroluminescent device SONY CORPORATION (JP) 2001-01-31 EP disclosed
US-5098987-A Polymers for fibers for reinforcement THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1992-03-24 US disclosed
US-5001217-A Crosslinkable rigid-rod benzobisazole polymers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1991-03-19 US disclosed
EP-0078503-B1 THERMOSETTING RESIN COMPOSITION AND PREPOLYMER THEREOF Hitachi, Ltd. (JP) 1986-02-26 EP disclosed
US-4448940-A POLYOXAZOLINES BASED ON DINITRILES AND DIEPOXY COMPOUNDS; POLYISOCYANURATE; FLEXIBILITY; PRINTED CIRCUITS HITACHI, LTD. (JP) 1984-05-15 US disclosed
EP-0078503-A1 Thermosetting resin composition and prepolymer thereof Hitachi, Ltd. (JP) 1983-05-11 EP disclosed