Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 10/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11926518 | 0.93 | PDK2 (0.38) | PDK2DUSP3LMNAMAPTHTT | |
| SCHEMBL11926642 | 0.90 | PDK2 (0.38) | PDK2DUSP3LMNAMAPTHTT | |
| SCHEMBL11926506 | 0.88 | PDK2 (0.39) | PDK2DUSP3LMNAMAPTHTT | |
| SCHEMBL12165796 | 0.87 | PDK2 (0.37) | PDK2MAPTHTTKDM4E | |
| SCHEMBL11926515 | 0.86 | CNR2 (0.38) | PDK2LMNAMAPTHTTCNR2 | |
| SCHEMBL12783147 | 0.85 | CNR2 (0.33) | PDK2DUSP3LMNAMAPTHTT | |
| SCHEMBL12165803 | 0.83 | PDK2 (0.34) | PDK2DUSP3LMNA | |
| SCHEMBL11926659 | 0.82 | PDK2 (0.37) | PDK2CNR2KDM4EALDH1A1 | |
| SCHEMBL13780984 | 0.82 | PDK2 (0.40) | PDK2LMNAMAPTHTTCNR2 | |
| SCHEMBL13781091 | 0.82 | PDK2 (0.39) | PDK2LMNAMAPTHTTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785636-B2 | Substituted indoloacridines for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| US-20120202997-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-08-09 | — | — | US | disclosed |
| US-20120202997-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202997-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | EPCAM, L1CAM, OR10J3 | PDK2 498/4885DUSP3 4654/4885LMNA 2700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.