Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ATP4A | P20648 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ATP4B | P51164 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10281586 | 0.85 | CYP3A4 (0.41) | CYP3A4CYP2D6LMNATSHRHRH2 | |
| SCHEMBL13109108 | 0.84 | CYP3A4 (0.41) | CYP3A4CYP2D6LMNATSHRHRH2 | |
| SCHEMBL20369115 | 0.81 | MEN1 (0.38) | CYP3A4CYP2D6LMNATSHRHRH2 | |
| Cimetidine SCHEMBL2873984 | 0.79 | SLC47A1 (0.69) | CYP3A4CYP2D6LMNATSHRHRH2 | |
| SCHEMBL11555931 | 0.79 | CYP3A4 (0.36) | CYP3A4CYP2D6LMNATSHRHRH2 | |
| Cimetidine SCHEMBL2873981 | 0.79 | SLC47A1 (0.69) | CYP3A4CYP2D6LMNATSHRHRH2 | |
| Cimetidine SCHEMBL10855569 | 0.79 | SLC47A1 (0.69) | CYP3A4CYP2D6LMNATSHRHRH2 | |
| Cimetidine SCHEMBL1163516 | 0.79 | SLC47A1 (0.69) | CYP3A4CYP2D6LMNATSHRHRH2 | |
| Cimetidine SCHEMBL10855575 | 0.79 | SLC47A1 (0.69) | CYP3A4CYP2D6LMNATSHRHRH2 | |
| Cimetidine SCHEMBL1093 | 0.79 | SLC47A1 (0.69) | CYP3A4CYP2D6LMNATSHRHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160024011-A1 | Multi-API Loading Prodrugs | ALKERMES PHARMA IRELAND LTD (IE) | 2016-01-28 | — | — | US | disclosed |
| US-20120202823-A1 | Multi-API Loading Prodrugs | ALKERMES, INC. | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024011-A1 | Multi-API Loading Prodrugs | AADAC, PAICS, ABCG2 | CYP3A4 69/4885CYP2D6 119/4885LMNA 2855/4885 |
| US-20120202823-A1 | Multi-API Loading Prodrugs | AADAC, PAICS, ABCG2 | CYP3A4 69/4885CYP2D6 119/4885LMNA 2855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.