Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 19/20 | 0.44 |
| ▸ | MC5R | P33032 | 3/20 | 0.40 |
| ▸ | MC3R | P41968 | 3/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | MC1R | Q01726 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11929574 | 0.86 | MC4R (0.47) | MC4RMC5RMC3RSLC2A1MC1R | |
| SCHEMBL11929564 | 0.86 | MC4R (0.50) | MC4RMC5RMC3RSLC2A1MC1R | |
| SCHEMBL11929584 | 0.85 | MC4R (0.45) | MC4RMC5RMC3RSLC2A1MC1R | |
| SCHEMBL11929590 | 0.84 | MC4R (0.42) | MC4RMC5RMC3RSLC2A1MC1R | |
| SCHEMBL11929586 | 0.84 | MC4R (0.52) | MC4RMC5RMC3RSLC2A1MC1R | |
| SCHEMBL4669868 | 0.84 | MC4R (0.45) | MC4RMC5RMC3RSLC2A1MC1R | |
| SCHEMBL11929587 | 0.84 | MC4R (0.43) | MC4RMC5RMC3RSLC2A1MC1R | |
| SCHEMBL8033767 | 0.81 | MC4R (0.46) | MC4RMC5RMC3RMC1R | |
| SCHEMBL8039643 | 0.81 | MC4R (0.44) | MC4RMC5RMC3RMC1R | |
| SCHEMBL8036015 | 0.80 | MC4R (0.49) | MC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236818-B2 | Substituted imidazopyridine derivatives as melanocortin-4 receptor antagonists | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2012-08-07 | — | — | US | disclosed |
| US-20100093697-A1 | Substituted Imidazopyridine Derivatives As Melanocortin-4 Receptor Antagonists | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093697-A1 | Substituted Imidazopyridine Derivatives As Melanocortin-4 Receptor Antagonists | MC4R, MC3R, MC5R | MC4R 1/4885MC5R 3/4885MC3R 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.