⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797086 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL307783 | 0.96 | — | — | |
| SCHEMBL28291982 | 0.83 | — | — | |
| SCHEMBL3287132 | 0.72 | — | — | |
| SCHEMBL27263729 | 0.72 | — | — | |
| SCHEMBL8797088 | 0.69 | — | — | |
| SCHEMBL47728 | 0.69 | — | — | |
| SCHEMBL27527949 | 0.67 | — | — | |
| SCHEMBL3280767 | 0.67 | — | — | |
| SCHEMBL1407387 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 429 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220235058-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING A BTK INHIBITOR | STA PHARMACEUTICAL HONG KONG LIMITED (CN) | 2022-07-28 | — | — | US | claimed |
| EP-2970291-B1 | PROCESSES AND INTERMEDIATES FOR PREPARING A MEDICAMENT | JANSSEN PHARMACEUTICA NV (BE) | 2022-05-11 | — | — | EP | claimed |
| CN-109761874-A | Preparation process of medical intermediate 4-nitroindole | 代可昕 | 2019-05-17 | — | — | CN | claimed |
| CN-105622483-B | A kind of synthetic method of 4- nitroindoline | 苏州艾缇克药物化学有限公司 | 2019-04-26 | — | — | CN | claimed |
| CN-109053534-A | A kind of preparation method of medicine intermediate 4- nitroindoline | 苏州盖德精细材料有限公司 | 2018-12-21 | — | — | CN | claimed |
| CN-105622483-A | Synthesis method of 4-nitroindole | ITIC MEDCHEM CO LTD | 2016-06-01 | — | — | CN | claimed |
| CN-103351326-A | Synthesis process of important pharmaceutical chemical intermediate 4-nitroindole | ZHANGJIAGANG WEISHENG BIOLOG PHARCEUTICAL CO LTD | 2013-10-16 | — | — | CN | claimed |
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | claimed |
| EP-0537543-A1 | 2-(2-(fluorophenyl)-1,3,4-thiadiazol-5-yl-oxy)-acetamides useful as herbicides | BAYER AG (DE) | 1993-04-21 | — | — | EP | claimed |
| EP-0516156-A1 | Chemical modification of 2\"-amino group in elsamicin A | Bristol-Myers Squibb Company (US) | 1992-12-02 | — | — | EP | claimed |
| US-4957935-A | Phenyltriazole derivative and insecticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-09-18 | — | — | US | claimed |
| US-4925935-A | BACTERICIDES | LEDERLE (JAPAN), LTD. (JP) | 1990-05-15 | — | — | US | claimed |
| US-4866171-A | THIENAMYCIN ANTIBIOTIC | LEDERLE (JAPAN), LTD. (JP) | 1989-09-12 | — | — | US | claimed |
| US-20240066047-A1 | ANTIBODY-DRUG CONJUGATES COMPRISING A CYCLIC DINUCLEOTIDE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-02-29 | — | — | US | disclosed |
| US-11666594-B2 | Antibody-drug conjugates comprising a cyclic dinucleotide | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-06-06 | — | — | US | disclosed |
| CN-111511737-B | Monocyclic beta-lactam compounds for the treatment of bacterial infections | 南京明德新药研发有限公司 | 2022-10-18 | — | — | CN | disclosed |
| US-4288450-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |
| US-4232030-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-11-04 | — | — | US | disclosed |
| US-4194047-A | Substituted N-methylene derivatives of thienamycin | MERCK & CO., INC. (US) | 1980-03-18 | — | — | US | disclosed |
| EP-0001264-A1 | Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone and their preparation | MERCK & CO. INC. (US) | 1979-04-04 | — | — | EP | disclosed |