Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 14/20 | 0.75 |
| ▸ | NAALAD2 | Q9Y3Q0 | 5/20 | 0.75 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4147358 | 1.00 | FOLH1 (0.75) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL14116981 | 0.88 | FOLH1 (0.57) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL11941053 | 0.88 | FOLH1 (0.57) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL1377049 | 0.87 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL14102890 | 0.87 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL14102870 | 0.87 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL18161468 | 0.87 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL12145776 | 0.87 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL17573317 | 0.86 | FOLH1 (0.90) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL13559304 | 0.85 | FOLH1 (0.64) | FOLH1NAALAD2RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150079001-A1 | IMAGING AGENTS AND METHODS OF IMAGING NAALADASE OR PSMA | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-03-19 | — | — | US | disclosed |
| US-8227634-B2 | Imaging agents and methods of imaging NAALADase or PSMA | POMPER MARTIN GILBERT (US) | 2012-07-24 | — | — | US | disclosed |
| US-20090117042-A1 | Imaging agents and methods of imaging NAALADase or PSMA | THE JOHNS HOPKINS UNIVERSITY (US) | 2009-05-07 | — | — | US | disclosed |
| US-7408079-B2 | Imaging prostate cancer | THE JOHNS HOPKINS UNIVERSITY (US) | 2008-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090117042-A1 | Imaging agents and methods of imaging NAALADase or PSMA | FOLH1, DNPEP, NAALAD2 | FOLH1 1/4885NAALAD2 3/4885RIMKLA 197/4885 |
| US-20150079001-A1 | IMAGING AGENTS AND METHODS OF IMAGING NAALADASE OR PSMA | FOLH1, DNPEP, NAALAD2 | FOLH1 1/4885NAALAD2 3/4885RIMKLA 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.