SCHEMBL11937580

SCHEMBL11937580

CC1C=CC=C2NC(=O)NC21

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
BACE1 P56817 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19157985 0.65 CRBN (0.40)
SCHEMBL7511152 0.64 BACE1 (0.33) BACE1
SCHEMBL24247847 0.61
SCHEMBL30995351 0.60 TDP1 (0.32)
SCHEMBL13785163 0.60 BACE1 (0.38) TSHRBACE1
SCHEMBL15876589 0.59
SCHEMBL21849454 0.58
SCHEMBL21428844 0.57
SCHEMBL23183091 0.57
SCHEMBL18754222 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2471876-A1 DICHLORODIKETOPYRROLOPYRROLE PIGMENT, COLORING MATERIAL DISPERSION CONTAINING THE PIGMENT, AND PROCESS FOR PRODUCTION OF THE COLORING MATERIAL DISPERSION FUJIFILM Corporation (JP) 2012-07-04 EP disclosed